MGL is the major degradative enzyme of 2-AG in the mouse brain

Immunofluorescence staining for MGL using two different antibodies recognizing independent epitopes of the MGL protein resulted in a comparable distribution pattern, although the general density of staining was stronger for the antibody “MGL-mid” in human hippocampal sections . Notably, as with the DGL-α-immunostaining, the distribution pattern of MGL mirrored the laminar structure of the hippocampal formation…