The difference between lived experience and official anti-cannabis propaganda raised a general skepticism toward state authority . Considering the growing awareness about the harmful effects of alcohol and tobacco consumption, the draconian measures against cannabis looked increasingly arbitrary and unreasonable. Cannabis supporters believed that prohibitory policies violated their constitutional rights to privacy and freedom of…
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One agriculturalist reported receiving death threats after selling water to cannabis cultivators
At the 2018 town hall, and numerous prior meetings, they emphasized their status as legitimate community members — veterans, citizens, consumers of county goods, local property owners, “good” growers and medical users — not nuisances, criminals, foreigners or outsiders. In interviews and public forums many Hmong-American cultivators expressed a desire to comply with the rules.…
Data among our participants seem to support this as only 30% of those who were HIV negative reported current PrEP use
Our finding that interruptions in mental health care directly linked to substance use, which in turn was linked to other negative outcomes, suggests that strategies to ensure continuity of care among this population are critical. The interruptions in care during the COVID-19 pandemic may be partly explained by loss of employment and subsequent loss of…
We hesitate to speculate about the potential role of these genes in the etiology of cannabis use disorders
The genes that surpassed gene-based correction were C17orf58, BPTF and PPM1D. PPM1D is in a region of chromosome 17 that is well documented to be amplified in breast cancer , and the gene itself belongs to a family of serine/threonine phosphatases that are involved in stress signaling . On the other hand, BPTF was originally…
Results suggest that marijuana use can act as a barrier to graduate degree completion
Verbal learning, memory, executive functioning, IQ, and attention, which are critical for academic success, are impaired by both acute and chronic exposure to marijuana . Arria, Barrall, Allen, Bugbee, and Vincent suggest that the immediate, rewarding effects of substance use might lead to a re-prioritization of academic pursuits that are associated with longer-term rewards. This study…
An overview of the participant recruitment strategy is described in detail elsewhere
Numerous choline-containing compounds contribute to the tCho signal measured in this study,complicating the interpretation of this sex difference.For example,phosphatidylcholine plays an important role in the phospholipid bilayer in cell membranes,and choline is essential in the formation of the neurotransmitter acetylcholine.Generally speaking,increases in choline signal in the brain have been demonstrated in cases with pathology.While this…
Cannabis is the most prevalent and increasingly used illicit drug in the United States
There are notable limitations to this study.As this is a pilot study,the authors acknowledge that future experiments will require more mice in each treatment group for an appropriately powered study.Assessments of the corpora cavernosa response to treatments were made based on histological and immunohistochemical changes.While these are adequate surrogates to determine how fibrosis can progress…
Study materials and procedures were approved by the University of Michigan Medical School Institutional Review Board
Taken together,findings underscore that alterations in cortical metrics are likely dynamic and influenced by age,pre-existing vulnerabilities,and exogenous factors such as marijuana use.Continuing to study associations between cortical metrics and substance use is important given estimates have been linked to cognitive functioning in several studies in our laboratory and others.Alcohol likely has similar deleterious consequences on the brain.The…
The idea of our model was to represent as near as possible “real world” conditions of human marijuana use
Cursory analyses with a cutoff of 1.5 shows apoptotic pathways as being significant for TSC exposure as well.It is important to note that the marijuana used for this study was obtained from a contracted supplier that provides marijuana for therapeutic use in Canada.It is grown under strictly controlled and documented conditions.Although this study has only examined smoke condensate from…
The coarse particles produced a naturally less dense material while the fine grade of shiv a naturally more dense material
In all cases the anisotropic internal structure of the material accounts for the clear variation in both mechanical and thermal properties of the material with testing direction. This is found to be most consistent in the thermal conductivity with a significantly lower thermal conductivity for all variations of hemp-lime in the parallel loading direction. As the…