McFadden’s pseudo-R2 was also calculated, comparing each model to the null model. The predictors considered in the multivariate models were age, severity of illness measured by the Acute Physiology and Chronic Health Evaluation II score, cumulative dose amounts of both opioids and benzodiazepines from time of first administration to a WS assessment day, days on both opioids…
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The report approvingly quoted a narcotics officer who claimed that “Marijuana has a worse effect than heroin
Our multiple-disciplinary approach, combining the PCR data with literary-historical analysis and AMS-based 14C dating of the textile samples, has enabled us to unearth this little known aspect of textile history e i.e. ancient hemp in the Land of Israel.Progress in the treatment of schizophrenia has been hindered by an inadequate understanding of the pathogenesis of…
The server component is also responsible for the storage of the collected information and the computation of derived scores
See Table 1 for all measures in the baseline and year 1 substance use module. Additional measures will likely be added starting at year 2 follow-up sessions.The first portion of the ABCD substance use protocol includes a brief introduction that operationalizes the term “drug use,” repeats that all answers are confidential, and then proceeds to ask…
California is the most populous state with the longest history of medical marijuana legalization in the US
Notably, as commonly seen with other CM studies, patients ultimately earned approximately 50-60% of the maximum amount available in prizes in the $560 condition but only approximately 25-30% of the maximum amount available in prizes in the $250 condition = 14.52, p <.001. This and other studies examining the effect of the magnitude of rewards on outcomes suggest that…
Alcohol misuse is one of the leading contributors to preventable mortality and morbidity worldwide
Prior studies from this laboratory found that vapor inhalation of THC using an e-cigarette based system decreases body temperature, with an observed nadir similar to the effects of 10-20 mg/kg THC, i.p. but with a duration of action that was much shorter . These studies also found anti-nociceptive effects of inhaled THC that were comparable in…
Previous animal studies have reported that alcohol enhances the absorption and delivery of MA in the brain
The recommendations for DSM-5 substance use disorders represent the results of a lengthy and intensive process aimed at identifying problems in DSMIV and resolving these through changes in DSM-5. At the same time, the variable amount of evidence on some of the issues points the way toward studies aimed at further clarifications and improvements in…
There are several possible explanations for the link between major depressive disorders and chronic marijuana use
Depressive disorders have been associated with morphological brain abnormalities, although the majority of studies have been conducted in adults. Reduced hippocampal volumes have been found among depressed adults , although this may be associated with age of onset and one found no hippocampal differences . White matter abnormalities have also been associated with increased depressive symptoms and…
A significant portion of MAUCRSA is comprised of testing rules that aim to certify cannabis safety
Variables believed to be con-founders for this study encompassed population level and individual level variables that may affect the exposure and the outcome.These variables included state’s cannabis regulatory status, state’s COVID-19 infection prevalence, state’s percent urbanicity, age, sex, and education.State’s cannabis regulatory status is hypothesized as a con-founder as state’s legalization may be associated with state’s…
The names of workers have been altered in order to protect the anonymity and confidentiality of respondents
While there are many studies that focus on cannabis consumers – health outcomes and public safety issues related to the legalization and use of cannabis – little attention has been paid to workers in the industry.The small amount of occupational safety and health literature that does exist regarding the cannabis industry focuses on the biological, chemical,…
The self-reported use further indicates the need to study cannabis to understand its potential risks versus benefits
The lack of significant adverse effects in this study encourages further investigation into the use of cannabis-based interventions including CBD to treat chronic SCD pain in prospective trials with a larger cohort over a longer duration.Questionnaire-based approaches have provided insight into the prevalence of cannabis use in the SCD community, and these studies have given first-hand…