People of all ages and backgrounds consume marijuana for a variety of reasons

Marijuana has a great cultural significance which is apparent in clothing, artwork, music, and many other forms.It is a constant and accessible commodity, even more so than alcohol to some, and has become deeply ingrained in California culture. Its accessibility makes it easy for people to use regularly and to create substance based relationships where…

The net balance of benefits and drawbacks from vaping-related apps likely depends on app content

Extrapolation of the results of this study is limited due to the small sample of women – pregnant or non-pregnant – tested in the ED for drugs and alcohol. An unknown portion of women with substance use may have been identified by history or observation and were not in need of additional testing. Additionally, in…

The all-inclusive model was then reduced one variable at a time to determine the best prediction model

McFadden’s pseudo-R2 was also calculated, comparing each model to the null model. The predictors considered in the multivariate models were age, severity of illness measured by the Acute Physiology and Chronic Health Evaluation II score, cumulative dose amounts of both opioids and benzodiazepines from time of first administration to a WS assessment day, days on both opioids…

The report approvingly quoted a narcotics officer who claimed that “Marijuana has a worse effect than heroin

Our multiple-disciplinary approach, combining the PCR data with literary-historical analysis and AMS-based 14C dating of the textile samples, has enabled us to unearth this little known aspect of textile history e i.e. ancient hemp in the Land of Israel.Progress in the treatment of schizophrenia has been hindered by an inadequate understanding of the pathogenesis of…

The server component is also responsible for the storage of the collected information and the computation of derived scores

See Table 1 for all measures in the baseline and year 1 substance use module. Additional measures will likely be added starting at year 2 follow-up sessions.The first portion of the ABCD substance use protocol includes a brief introduction that operationalizes the term “drug use,” repeats that all answers are confidential, and then proceeds to ask…

California is the most populous state with the longest history of medical marijuana legalization in the US

Notably, as commonly seen with other CM studies, patients ultimately earned approximately 50-60% of the maximum amount available in prizes in the $560 condition but only approximately 25-30% of the maximum amount available in prizes in the $250 condition = 14.52, p <.001. This and other studies examining the effect of the magnitude of rewards on outcomes suggest that…

All behavioral responses were automatically recorded by Med Associates software

Most of the imputation strategies resulted in a significant improvement in estimates of substance use data when compared to estimates relying on complete case data, which was especially true in the case of a ‘rare’ outcome such as heroin use. However, MI performed the most favorably regardless of the prevalence of the outcome or the level…

Previous animal studies have reported that alcohol enhances the absorption and delivery of MA in the brain

The recommendations for DSM-5 substance use disorders represent the results of a lengthy and intensive process aimed at identifying problems in DSMIV and resolving these through changes in DSM-5. At the same time, the variable amount of evidence on some of the issues points the way toward studies aimed at further clarifications and improvements in…

Initiating marijuana use in early adolescence is an important prognosticator for subsequent drug dependence

Data collection on state medical marijuana laws included gathering all state statutes and subsequent regulations, and validating information against publicly available data sources and through telephone calls with state officials. Throughout the study, we conducted regular updates to monitor changes in regulations and amendments to state laws . Analyses incorporated a dichotomous measure reflecting whether…

A significant portion of MAUCRSA is comprised of testing rules that aim to certify cannabis safety

Variables believed to be con-founders for this study encompassed population level and individual level variables that may affect the exposure and the outcome.These variables included state’s cannabis regulatory status, state’s COVID-19 infection prevalence, state’s percent urbanicity, age, sex, and education.State’s cannabis regulatory status is hypothesized as a con-founder as state’s legalization may be associated with state’s…