The most interesting characteristic of the oil obtained from C. sativa seed is the high content of polyunsaturated fatty acids , represented especially by linoleic and α-linolenic acids. Moreover, it has been reported that unsaponifiable fraction provides health benefits , in fact minor lipid components are of great interest because they affect the nutritional value…
The higher solubility of hemp samples might also be attributed to its richer content of chaotropic salts
In addition, the bands corresponding to the acidic and basic subunits of edestin are still visible under non-reducing conditions, although with lower intensity. At both reducing and non-reducing conditions, minor bands at ≤10 kDa were identified as the water-soluble 2S albumin storage protein, which consists of 2 subunits of 7 and 3 kDa linked by…
Most of the studies on the toxicity of marijuana use during pregnancy have evaluated the neuro-behavioral effects
The elevated risk rapidly declined thereafter. Increased release of catecholamines caused by marijuana can enhance normal or abnormal automaticity inside the heart and subsequently cause PVCs, which in turn, will reduce diastolic time.The reduction in DT in combination with the direct vasoconstrictive effect of marijuana, will potentially lead to “physiologic” slow blood flow in coronary…
There is also pharmacological evidence that cannabinoids alter nicotinic-acetylecholinergic receptor response
An intermediate, reduced set of items considered in the subsequent analyses are presented in Table 2. In prediction analyses with early-onset marijuana use as the outcome, the most predictive items were three externalizing characteristics: destroys things belonging to his/her family or others,steals outside the home,and lying or cheating.We used these items to construct a preliminary…
It was important to determine whether the association with marijuana use was due to concomitant cigarette smoking
The number of episodes of marijuana use over 3 months was also recorded at 15 weeks and 20 weeks of gestation. Other drug use was also recorded, including cocaine, amphetamines, substance 1 a scale between 10 and 90 generated using an algorithm involving age, income and education. A higher score indicates higher socioeconomic status.It is a…
They found that marijuana use was associated with smaller volume of the left amygdala and right ventral striatum
Increased RD has been related to demyelination in neurodegenerative diseases such as multiple sclerosis,suggestive of a neurotoxic effect with early age of first use of marijuana. These findings taken together, and in line with previous studies,suggest that an earlier age of onset is associated with decreased coherence of white matter. Moreover, these results suggest that…
Non-infectious pulmonary diagnoses were more common in both marijuana and tobacco smokers
We found a main effect of group on net IGT scores, such that MJ+ had overall lower net IGT scores than HC. These findings may highlight differences in decision-making performance between young adult MJ+ and HC. Results from this study underscore the importance of interventions targeted at reducing risky decision-making in young adult MJ users.…
Newspapers have largely described marijuana legalization as a law enforcement issue rather than an economic issue or a medical issue
In a follow-up study in 2014, the whole blood of donors who had consumed cannabis had diminished platelet aggregation. The conclusion was drawn that endocannabinoid receptor agonists reduce platelet activation as well as aggregation, and as such might have potential in antithrombotic therapies. This anticoagulatory effect could counteract the surgeon’s attempts to create hemostasis within…
Education plays a crucial role in reducing stigmas associated with cannabis consumption
Factors informing opinions of cannabis use may include generational cohort, religious affiliation, media exposure, prior or current prescription and illicit drug use, and political affiliation. However, even as attitudes toward cannabis have improved, there remains a significant stigma attached to cannabis that needs to be addressed. Even though medicinal cannabis was legalized in California over 20…
We have weighted the impact of polysubstance use in relation to CAN in the context of HIV
We have identified a significant number of binding motifs to BHLHE40, BACH1, SPl1, NFKB1 , JUND, CEBPE, SRF, PRDM14, ATF4 and USF2. Mapping of genes regulated by these factors have revealed sub-clusters characterized by co-regulation. Interestingly, the visualization of effects of cannabis alone and of cannabis in the context of HIV suggests that the genes most affected by…