Future research should examine process coding in BMIs that do discuss marijuana use to explore possible in-session processes that may be related to changes in marijuana use and can be targeted in future interventions. Similarly, although alcohol and marijuana use share similar predictors , they may differ in their mechanisms of change. For example, the…
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Examining cooccurrence in this setting addresses several important gaps in the existing literature
The second study found a cognitive behavioral therapy informed computer game to have comparable effectiveness to in person counseling in reducing depressive symptoms among adolescents. The third study found that adolescents with depressive symptoms who received motivational interviewing from their providers were more likely to participate in a web based cognitive behavioral therapy program designed to prevent worsening…
The olfactory mucosa is composed of the olfactory epithelium and the underlying olfactory neurons
In Denmark, both n-butanol and hydrogen sulfide are used to calibrate panelists, and the Japanese method uses five odorants in its panelist aptitude test . The use of multiple odorant standards may have advantages. Observations from related fields provide insights for environmental odor exposure assessment. Setting odor source minimum-distance setbacks and emission rates did not…
Substance use history of PSU participants was assessed at baseline with a semi-structured interview developed in-house
Furthermore, poorer executive function in abstinent abusers of several substances has been related to the amount of cocaine and cannabis consumed , suggesting clinically relevant consequences of chronic substance use. Despite extensive research into the neurocognitive correlates of substance abuse, only few studies investigated neurocognition in PSU relative to the more extensively studied AUD, and…
Similar concentrations of the compound also increase the frequency of miniature EPSCs in the spinal cord
The regulation of glutamatergic neurotransmission may also contribute to the antinociceptive activity of cannabinoid agonists. In the dorsal horn of the spinal cord, these agents suppress glutamate release from primary sensory afferents. Whole cell patch-clamp recordings in substantia gelatinosa neurons have indeed demonstrated that cannabinoid agonists reduce both the amplitude and frequency of spontaneous EPSCs…
A quantitative summary of the distribution of cannabinoid binding sites in the rat brain has been provided
2-AG may be produced by CA1 pyramidal cells during Schaffer collateral stimulation , and the newly generated endocannabinoid may mediate depolarization-induced suppression of inhibition , if able to diffuse to the nearby GABAergic boutons, or a suppression of excitation . Thus MGL is exquisitely poised to terminate the actions of 2-AG at hippocampal synapses.In a…
Linking biology with socially valued behavioral outcomes can be politically sensitive
The degree to which the genetic associations documented here for AAB are also associated with child or adolescent antisocial behavior is not clear. The results from this study provide an empirical starting point for subsequent developmental analyses to examine these questions. Fifth, there are likely to be aspects of the environment that moderate genetic influences…
Scales were correlated with measures from the same wave for convergent and discriminant validity analysis
Such real-time reports and ecological momentary assessments are becoming increasingly feasible as mobile and web technologies grow and advance . Obtaining EMA data via cellular phones has become increasingly popular and has already been used to collect information about alcohol and drug use as well as ART adherence among PLWHA. EMA for both alcohol/drug use and medication adherence…
A comparison of two intensity methods commonly used to evaluate single odorants were compared
The results of these three approaches are dramatically different because the fixed intercept forces all lines to the same point while the floating intercept allows for very different linear fits to the data. Further research is needed into the equation that best fits the relationship between concentration and intensity scales.The predicted ODTC50 using the 0-12 scale…
Exposures to environmental odors often result in complaints that local air inspectors must address
By contrast, it could reflect the increased prevalence of DM with age and the ability to detect an association with a lesser sample size when there is a greater cohort at risk for DM. The possible association of light marijuana use with decreased DM is similar to that of alcohol on DM and the metabolic syndrome,…