The primary independent variable was serum Vitamin D measured at ED enrollment. We used Vitamin D level at ED presentation to identify patients with pre-existing Vitamin D deficiency prior to hospitalization for an acute illness. Vitamin D deficiency was defined as a serum Vitamin D concentration <20 milligrams per deciliter .We collected blood in citrate…
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The scenarios for the pre-test and the post-test were different in order to avoid memorization bias
The second difference is the comparison of scores from a group of control hospitals in the same time frame. Finally, we used the second difference from the control group to rule out the part of the first score difference that is not influenced by GBR. This allowed us to estimate the treatment effect within the…
A better research agenda is needed to assess the impact of triage questions on patient care
Additional research could evaluate whether the additional screening questions distract the triage nurse from his or her primary goal of assessing acuity and contribute to inconsistency in triage assessments. If nurses were liberated from the mandated questions, they could potentially have more time for one-on-one patient care and other aspects of patient care, such as medication…
The effects of youth unemployment also inflict large economic costs on society
Research is needed to help governments minimize youth labour market disengagement . In the United Kingdom and Europe, social research and policy making around youth unemployment has focused on a particular subset of young people: Those who, in the transition out of compulsory schooling, find themselves not in education, employment, or training . We report data from…
Self-administration tasks have also been used extensively in developing effective AUD pharmacotherapies
Functional consequences of adolescent heavy drinking are seen in attenuated frontal cortex response during spatial working memory , and deficits on neuropsychological measures of attention , information retrieval , and visuospatial functioning , with some studies showing sustained effects into adulthood . Drinking so much that hangover or withdrawal symptoms are experienced is associated with…
Purified subsets were prepared from primary PBL using lineage-specific mAb and magnetic nanoparticles
No one has been able to characterize CB2 at a different locations of the cell other than the cell surface. If CB2 does exist at different locations, there is currently no evidence as to whether these receptors are functional or not. This gap in the field was mostly due to a lack of a set…
This series of analyses was repeated for self-reported nicotine use in the year before and during pregnancy
Past-month alcohol and nicotine use is most common during the first trimester of pregnancy , during which time women may not realize that they are pregnant. Although healthcare systems are well poised to screen women of reproductive age for substance use, it is challenging to predict which women are at risk for using nicotine and…
The observed high correlation of alcohol and marijuana use may be due to a shared genetic risk for drug use
The availability of these services may have been especially important among SGM participants within our study population, as previous studies have shown that SGM youth experiencing homelessness are more likely to utilize service programs, such as STI and HIV testing, food access, street outreach teams, and counseling services compared to their heterosexual cisgender peers. Though…
Human immunodeficiency virus infection is often accompanied by chronic fatigue and disrupted sleep patterns
As such, these results reflect self-reported symptoms, and the extent to which they generalize to psychiatric diagnoses is unclear. Future work utilizing structured clinical interviews are warranted to identify diagnoses associated with conventional and ecigarette use. This is first the investigation to characterize adolescent psychiatric comorbidity in an era when the extensive popularity of e-cigarettes…
The logistic regression model used to simulate the probabilities of BLQ concentrations found that TAD was significant
Two key modifications were made to the published model based on information presented by Bansal et al.. First, the percent contributions of cytochrome P450 and UGT enzymes to CBD clearance were redefined as 20% and 80%, respectively, based on updated in vitro human liver microsome studies. Second, UGT1A7 was removed as an important contributing enzyme…