All analyses were conducted using SAS R version 9.3 and adjusted by weights generated using RDSAT version 7.1.46 to reflect better population estimates. Descriptive statistics include crude frequencies and RDS-adjusted population parameters, the latter of which will be reported in-text. Multi-variable logistic regression was used to identify covariates for both dependent variables. AUDIT and HADS variables were…
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The contributions of vascular and inflammatory processes to NCI in this study were profileand domain-specific
Given these similarities and the aging HIV population, there is a heightened need to distinguish vascular from non-vascular presentations of HAND, though the standard method of classifying HAND using Frascati criteria would not be able to distinguish the two phenotypically . Together these findings have generated increased interest in vascular contributions to NCI in ART-treated PWH…
More information regarding the promotional campaign can be found in the published protocol
Importantly digital therapeutics do not need to have a siloed focus on SUD treatment . Indeed, we have the opportunity to maximally benefit from what digital technology offers to embrace the co-occurring needs of patients. Digital therapeutics can arguably embrace whatever combination of needs a patient may have. They may focus on, for example, SUD…
Critical studies of ethnicity and substance use illustrate the relevance of socially-ascribed identity categories
An individual’s ability to choose an identity is constrained by social structure, context, and power relations. Structural constraints on identity formation cannot be ignored, as people do not exist as free floating entities but instead are influenced and constrained in various ways by their socioeconomic and geographical environment . As such, an identity is not…
Alcohol use was also not biologically verified in this study
As such, the present study may have been under powered to detect small effects sizes, which may account for the null findings regarding intervention effects on drinking outcomes. Future studies are encouraged to recruit larger samples of non-treatment seeking participants to better detect small effects. Furthermore, this finding should be considered in light of the sample,…
Endocannabinoids are also involved in the regulation of neuronal excitability
Ion channels are macromolecular pores in cell membranes that play a principal role in regulating the electrical properties of membranes and cellular excitability, thence enabling neurotransmission, sensory transduction, cognitive function, heart rhythm, motor movement, hormone secretion, reproduction, stress adaptation, and cell protection, processes crucial to sustain life. Ion channel proteins are subject to post translational modulation…
Aim 1b examined the relationship between continuous delayed recall and the three regions of interest
Post hoc delayed recall analyses were conducted that excluded participants who were excluded in post hoc analyses in aim 1 as well as those not consistently on ART and participants with a substance use disorder during follow-up. The total included after these exclusions was n=55. A single mediator model was used to investigate if medial temporal…
Of particular interest to this study is a common polymorphism involving a Val to Met substitution at codon
These studies make it difficult to ascertain whether alcohol or nicotine use/dependence account for previous findings, as their individual contributions to gray matter structure or brain activity were not examined. Thus, it is critical to investigate the unique contributions of alcohol and nicotine use to brain morphometry in heavy drinking smokers. We hypothesized that there…
Model fit was then explored using the Akaike Information Criterion model fit index
Mortality due to prescription drug use is a significant cause of death in the United States, accounting for 36% of all poisoning deaths in 2007, a number that tripled from 1999 to 2007 . It is estimated that0.04% of individuals receiving a prescription opioid have a fatal overdose, with the odds of mortality higher among…
The analysis for differences in 16 categories raises the question of the multiple comparisons problem
Unfortunately, limiting space may also limit the room for positive evaluation and strings of praising adjectives.However, while implicit bias exists, employing limits in response format may rein in the manifestation of implicit bias by focusing the writer.This was a single center study; only SLOE narratives from applicants who applied to interview at a single, academic…