Acute cardiovascular effects of marijuana include tachycardia and orthostatic hypotension

Other studies have demonstrated that cannabis oils may improve the pain and spasticity associated with multiple sclerosis.There is also evidence marijuana may be useful in treating nausea and vomiting associated with cancer and a recent trial demonstrated that cannabidiol is effective in the treatment of refractory epilepsy of childhood. However, the effectiveness of marijuana in the…

Previous studies have found a strong positive association between cigarette and marijuana use

Future studies might attempt to identify potential premorbid characteristics that contribute to brain function abnormalities among marijuana users, such as additional facets of personality and psychological functioning, genetic markers, and hormonal influences. In addition, emerging evidence suggests shifts in neural processing during the initial stages of abstinence, and longitudinal examinations are needed to elucidate the…

Participants were asked to press a button when they saw a design with a dot

Adult studies of working memory have consistently revealed prefrontal and posterior parietal cortical activation in response to intact performance during working memory tasks . In contrast to the large number of fMRI studies in adult populations, very few studies have examined fMRI response to working memory tasks in typically developing adolescents, and most have focused…

The state sought a variety of stakeholder perspectives to develop principles for the policy framework

As early adopters of recreational marijuana legalization, these states set precedents for other states to follow suit, even though marijuana remained an illegal substance under federal law. In both Colorado and Washington, local governments could enact ordinances or regulations to limit the availability of local marijuana facilities, including prohibiting them altogether.Colorado and Washington serve as quasi-natural…

Marijuana may be expected to cause respiratory symptoms

Craving and withdrawal symptoms were highest during the first week of the protocol and decreases were observed within the first two weeks of abstinence. We speculate slight increases on these scales toward the end of the protocol are related to anticipation of reinitiation of marijuana use. Follow-up interviews were not conducted past 28-days; therefore, plans…

A higher peak exposure limit gave a lower frequency of exceedance at each distance

It also reduced the separation of the 3 frequency distributions. In addition to the average concentrations, the stronger mechanical air mixing made the transient concentrations become more uniformly distributed in space. Concentration peaks at each distance become much less likely to occur in the outdoor settings than indoors. For example, for both smoking and vaping, less…

Participants reported the appeal of electronic vaporisers for nicotine and marijuana

Nationally, young adults have the highest rates of current marijuana use, with 18.9% aged 18–25 years using in 2013, compared to 7.1% aged 12–17 years and 5.5% aged ≥26 years.According to 2014 data, almost 30% of young adults in Colorado reported current marijuana use.Young adults also have the highest current rates of tobacco smoking .More young…

There may also be complementarity in the usage of marijuana and alcohol

In addition, to the extent that use of one substance affects the usage of another among adolescents, accounting for this interdependence in substance use is important as it can minimize the possibility of obtaining spurious relationships and possibly biased model estimates. While some studies indicate that cigarette smoking is a strong predictor of the concurrent…

Modifications to the surfaces were made as necessary to correct for tissue misclassifications

However, this finding was only significant in women and was weaker and no longer significant after bronchodilator use. In the same birth cohort at age 45, Hancox et al further reported a significant negative association of marijuana joint years with forced expiratory flow at 25% and 75% of the pulmonary volume, but this association was…