Approximately nine percent of adults reported consuming cannabis in some form at least once a month. Based on a survey about frequency of use, Light et al. estimate that the total marijuana demand in the state is 121.4 metric tons annually . According to their methodology, individuals that consume cannabis daily constitute about one-fifth of…
All posts in July 2023
A single item assessed currently taking prescribed medications for a psychiatric diagnosis
A study found that people were significantly more likely to disclose personal information to artificial intelligence when they believed it was computer- rather than human-monitored. Users can develop a strong therapeutic alliance in the absence of face-to-face contact, even with a nonhuman app. Digital environments can promote honest disclosure due to greater ease of processing…
The supernatant was decanted and reserved as the cytoplasmic fraction
The column was washed several times with TBS and 0.1 x TBS to remove any unbound molecules. Finally the column was eluted with 0.1M glycine-Cl pH2.5. 6ml of this 0.1M glycine-Cl pH2.5 was added to the column, and each sequential 800μl was collected separately. There were two guinea pigs murdered for this experiment designated 13…
It has been proposed that there are in fact four alleles of a single sex determination locus in U. dioica
Cannabis spp. on the other hand has true sex chromosomes that exist as a heterochromatic pair where XX defines female and XY defines male. Cannabis was known in the literature to be under XY control as early as 1927 when female plants were damaged by having branches removed at an early stage of blooming, giving…
Slow dose titration and ongoing patient monitoring is also recommended
However, use of GHB as a recreational drug raises concern regarding the abuse potential of SMO. Indeed, in another clinical study with a sample of 48 participants, craving for SMO was observed in 10% of participants with psychiatric comorbidities, indicating that patients may be at risk of developing craving for and abusing SMO. SMO may…
Chronic liver disease modulates hepatic cannabinoid receptor expression
Currently marijuana has been legalized for medicinal and/or recreational use in 23 US states, as well as the District of Columbia, and its use in HIV/HCV-coinfected patients is common. Given that it is becoming more widely available and more regularly consumed, it is critical to assess its clinical effects, including any negative impact of THC…
HIV has been shown to cause significant impairments of varying severity in higher order brain functions
Lower UPSA-2 scores were related to lower education and WRAT-4 scores both in this study and the Blackstone et al. report, but in contrast to that study, our HIV+/ METH+ participants did not have lower education and WRAT-4 scores than the METH− groups, reflecting relatively intact premorbid intellectual functioning, or “cognitive reserve”, in the dually-affected…
A statistical correction was incorporated for the number of effective tests
By collecting samples immediately after and 30 min. after TSST onset, we were able to collect saliva samples when cortisol levels were expected to increase post-TSST and increased our chances of capturing peak cortisol response in line with previous guidelines . Samples were frozen at -80oC and later thawed and assayed in duplicate using commercially…
The developing brain is not thoroughly studied due to ethical concerns
The prevalence of substance use in the past three months was: 47% for cannabis, 33% for cocaine, 29% for methamphetamine, 26% for hallucinogens, 19% for sedatives, 13% for prescription opioids, 12% for street opioids, 10% for prescription stimulants, 7% for inhalants, and 3% reported the use of other substances, including: “belladonna”, “Hawaiian plant”, “native ritualistic…
Mediators can be defined as mechanisms through which one variable might achieve its effects
It was demonstrated that individuals at CHR report significantly more trauma and bullying than healthy controls. Further, those CHR subjects who experienced past trauma and bullying are more likely to have increased levels of depression and anxiety and a poorer sense of self. Importantly, higher levels of total childhood trauma were demonstrated to be associated…